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The Space Between: Connecting the Science of Targeted PsA Therapies to Patient Care

The Space Between: Connecting the Science of Targeted PsA Therapies to Patient Care

Improving care for patients with psoriatic arthritis is profoundly boosted by facilitating better patient-provider communication and implementing targeted treatment strategies. This activity took participants on a journey to look into the space between science and practice to enhance participants’ adeptness through innovative experiential learning and presentations. The expert presenters demonstrated mechanisms of action of therapies using a HoloLens—a mixed-reality device. They also discussed effectiveness and safety of existing and emerging targeted treatments for psoriatic arthritis and modeled a patient-provider shared decision making conversation. Learners gained expertise in the main pathways of immune activation and build inspiration to translate recent scientific advances into patient-centered care.

  • Dr. Deodhar, Professor of Medicine, Oregon Health & Science University

    Atul A. Deodhar, MD, MRCP, FACR, FACP
    Professor of Medicine,
    Medical Director of Rheumatology Clinics,
    Division of Arthritis & Rheumatic Diseases
    Oregon Health & Science University
    Portland, Oregon

  • Dr. Desai, Chief of Rheumatology, University of California, Irvine

    Sheetal Desai, MD, MSEd
    Chief of Rheumatology,
    Rheumatology Fellowship Program Director,
    Director, Lupus Clinic
    Associate Clinical Professor of Medicine,
    Division of Rheumatology
    University of California, Irvine
    Irvine, California

  • Joseph Merola, MD, MMSc
    Associate Professor, Harvard Medical School
    Vice Chair of Clinical Trials and Innovation, Dermatology
    Director, Center for Skin and Related Musculoskeletal Diseases
    Director, Clinical Unit for Research Innovation and Trials (CUReIT), Dermatology
    Departments of Dermatology and Medicine
    Division of Rheumatology
    Associate Program Director, Combined Medicine-Dermatology Residency Program
    Brigham and Women’s Hospital
    Boston, Massachusetts

Disclosure and Conflict of Interest Resolution

Educational activities provided by Forefront Collaborative must demonstrate balance, independence, and scientific rigor. All those in a position to control the content of an activity must disclose all relevant financial relationship(s) with commercial interest(s)*. For this educational activity, all conflicts of interest have been resolved through peer review and revisions to ensure independence, evidence base, fair balance, and absence of commercial bias. Disclosures appear below as they were at the launch of this activity.

*The ACCME defines a commercial interest as any entity producing, marketing, reselling, or distributing health care goods or services consumed by or used on patients. The ACCME does not consider providers of clinical service directly to patients to be commercial interests – unless the provider of clinical service is owned, or controlled by, an ACCME-defined commercial interest.

The following individuals have indicated that neither they nor their spouses/partners have had, in the past 12 months, financial relationship(s) with commercial interests relative to the content of this CME activity:

  • Planners (Forefront Collaborative): Marianna Shershneva, MD, PhD,  Stephanie Bartelt, PMP, and Sydney Pate, MS 
  • Planner: Alfred Martin, MD  
  • Planner: Svetlana Dambaeva, MD  
  • Planner: Linda Grinnell-Merrick, MS, NP-BC 

The following individuals have disclosed that they and/or their spouse/partner has had a financial relationship in the past 12 months: 

  • Planner: April W. Armstrong, MD, MPH has received a consulting fee from Abbvie, Janssen, Eli Lilly, Pfizer, Ortho Dermatologics, Sanofi Genzyme Regeneron, Bristol-Myers Squibb, Dermavant, Science 37, Modernizing Medicine, LEO Pharma, and Novartis. Dr. Armstrong has contracted research for Janssen, Eli Lilly, UCB Biopharma, Dermira, Bristol-Myers Squibb, LEO Pharma, Novartis, and Kyowa Hakko Kirin. 
  • Planner: Philip J. Mease, MD has received a consulting fee for AbbVie, Amgen, Bristol Myers Squibb, Boehringer Ingelheim, Celgene, Galapagos, Gilead, Janssen, Lilly, Novartis, Pfizer, Sun, and UCB. Dr. Mease has participated on a speaker’s bureau for AbbVie, Amgen, Bristol Myers Squibb, Celgene, Genentech, Janssen, Lilly, Novartis, Pfizer, and UCB and has contracted research for AbbVie, Amgen, Bristol Myers Squibb, Celgene, Janssen, Lilly, Novartis, Pfizer, Sun, and UCB.  
  • Presenter: Sheetal Desai, MD, MSEd has received a consulting fee for Janssen and has participated in a speaker’s bureau for Janssen. 
  • Presenter: Atul A. Deodhar, MD, MRCP, FACR, FACP has received a consulting fee for AbbVie, Amgen, Boehringer Ingelheim, Bristol Myers Squibb, Eli Lilly, Glaxo Smith & Klein, Janssen, Novartis, Pfizer, and UCB. Dr. Merola has participated on an advisory board for AbbVie, Boehringer Ingelheim, Bristol Myers Squibb, Eli Lilly, Glaxo Smith & Klein, Janssen, Novartis, Pfizer, and UCB; he has contracted research for AbbVie, Boehringer Ingelheim, Bristol Myers Squibb, Eli Lilly, Glaxo Smith & Klein, Janssen, Novartis, Pfizer, and UCB 
  • Presenter: Joseph Merola, MD, MMSc is a consultant for Merck Research Laboratories, Abbvie, Dermavant, Eli Lilly and Company, Novartis, Janssen, UCB, Celgene, Sanofi Regeneron, Almirall, Sun Pharma, Biogen, Pfizer, Incyte, Aclaris, and EMD Sorono. Dr. Merola is also an Investigator for Leo Pharma and Kyowa Kirin.   

As a result of participation in this educational activity, participants should increase their ability to:

  • Describe

    Describe a current model explaining psoriatic arthritis (PsA) pathophysiology and mechanisms of action of targeted therapies for PsA

  • Apply evolving treatment strategies and evidence of effectiveness and safety of targeted therapies for management of patients with PsA 

  • Discuss

    Discuss the impact of different PsA disease domains on the patient’s quality of life and patient-reported outcomes measures 

  • Engage patients with PsA in shared decision making regarding treatment goals, treatment plan, and treatment modification 


Unless otherwise specifically prohibited, you may temporarily download one copy of the materials for personal, noncommercial use only. You may not modify or copy the materials, use them for any commercial purpose or public display (commercial or noncommercial), remove any copyright or other proprietary notations, or transfer the materials to another person or online site.

Instructions for Claiming Your CME Certificate

If you attended this live activity, please complete an online version of the evaluation to download your CME certificate today. Evaluations must be completed by Friday, November 22, 2019. The online evaluation system will close after this date and no further certificates will be issued.


To receive your CME certificate or your certificate of participation, you MUST complete the online evaluation form after the live activity occurs.

Your certificate will populate immediately upon completion of the evaluation, so be ready to print and/or save your certificate at that time.

To gain access to the evaluation, you will be asked to create an account or to log in if you have a previous account with Med+Ed Manager. A copy of your certificate will be available in the account you created and can be accessed at any time through your dashboard.

Activity Information

Target Audience
The target audience for this activity was rheumatologists and NP/PA rheumatology providers. Other healthcare professionals who treat patients with PsA may have benefited from participation.

Accreditation Statement
Forefront Collaborative is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation Statement
Forefront Collaborative designated this live activity for a maximum of 1.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.25 Medical Knowledge MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

CME Content Review
The views and opinions expressed in this activity are those of the faculty and do not necessarily reflect the views or recommendations of Forefront Collaborative or Lilly.

The content of this activity was independently peer reviewed by two reviewers and two patients with psoriasis and psoriatic arthritis. The reviewers of this activity have no relevant financial relationships to disclose.

This continuing medical education activity included reference(s) to unlabeled or unapproved uses of drugs or devices.

This activity is provided by Forefront Collaborative.

Commercial Support
This activity is supported by an educational grant from Lilly. For further information concerning Lilly grant funding, visit www.lillygrantoffice.com.